The Tests They Don't Order
What's Actually Going On Inside You — And Why No One's Looking
The Problem
Modern medicine is reactive, not investigative.
They wait for something to break. High blood pressure? Here's a pill. Tumor? Here's chemo. Fatigue? You're probably just stressed.
What they don't do is ask why. Why is your blood pressure high? Why did the tumor develop? Why are you exhausted at 2pm every day?
The tests that could answer those questions exist. They're available. They're not experimental. But your doctor probably won't order them — because they're not "standard of care," insurance pushes back, and the system isn't built to find root causes. It's built to manage symptoms.
The alternative and functional medicine world runs these tests routinely. The conventional world scoffs at them — until the research catches up and suddenly it's obvious.
You don't have to wait for them to catch up.
What They Test vs. What Matters
| What They Test | What They Miss |
|---|---|
| Total cholesterol | Particle size, oxidized LDL, Lp(a) |
| Fasting glucose, maybe A1C | Fasting insulin, HOMA-IR (insulin resistance) |
| TSH (thyroid) | Free T3, Free T4, Reverse T3, antibodies |
| "Testosterone" (maybe) | Free T, SHBG, estradiol, full hormone panel |
| Basic metabolic panel | Magnesium RBC, zinc, B12, ferritin, D |
| Nothing for inflammation | hs-CRP, homocysteine, fibrinogen |
| Nothing for allergies | IgG food sensitivity panels |
| Nothing for toxins | Heavy metals, mold markers |
| Nothing for gut health | Comprehensive stool analysis, microbiome |
The standard panel tells you if you're about to die. It doesn't tell you why you feel like shit or what's quietly building toward a future problem.
Tests Worth Asking For
Inflammation Markers
Chronic inflammation is the common thread in heart disease, cancer, diabetes, autoimmune conditions, and neurodegeneration. If you don't measure it, you can't address it.
- hs-CRP (high-sensitivity C-reactive protein) — General inflammation marker. Elevated levels associated with cardiovascular risk and cancer.
- Homocysteine — Amino acid linked to inflammation and cardiovascular disease. Elevated by B-vitamin deficiencies.
- Fibrinogen — Clotting protein that increases with inflammation.
- ESR (sed rate) — Non-specific inflammation marker.
Full Hormone Panel
"Normal" testosterone ranges are based on population averages that include sick, sedentary, obese men. What's normal isn't optimal. And testosterone alone doesn't tell the full story.
- Total Testosterone — What most doctors test, but only part of the picture.
- Free Testosterone — The usable portion. Often low even when total is "fine."
- SHBG (Sex Hormone Binding Globulin) — High SHBG binds testosterone, reducing what's available.
- Estradiol (E2) — Men need some, but excess causes problems. Aromatase converts T to E.
- LH & FSH — Signals from pituitary. Help diagnose primary vs secondary hypogonadism.
- DHEA-S — Precursor hormone, declines with age.
- Cortisol — Stress hormone. Chronic elevation tanks testosterone.
- Prolactin — Elevated levels suppress testosterone.
Thyroid (Complete)
Doctors test TSH and call it done. But TSH can be "normal" while you're functionally hypothyroid. You need the full picture.
- TSH — Standard test, but just the signal from pituitary to thyroid.
- Free T4 — Storage hormone, what thyroid produces.
- Free T3 — Active hormone, what your body actually uses.
- Reverse T3 — Inactive form that blocks T3 receptors. Elevated by stress, inflammation, dieting.
- TPO & TG Antibodies — Detect autoimmune thyroid (Hashimoto's) often years before TSH goes abnormal.
Metabolic / Insulin
Diabetes is diagnosed by elevated glucose. But insulin resistance — the precursor — can be present for years while glucose stays normal. By the time glucose is high, the damage is done.
- Fasting Insulin — Should be low (under 5-6 μIU/mL ideal). High fasting insulin = insulin resistance even with normal glucose.
- HOMA-IR — Calculated from fasting glucose and insulin. Measures insulin resistance directly.
- Fasting Glucose — Standard, but late indicator.
- HbA1c — 3-month average blood sugar. Useful but not the whole story.
Nutrient Status
Deficiencies cause vague symptoms — fatigue, brain fog, weakness, poor immunity — that get blamed on stress or aging. Most doctors don't test.
- Vitamin D (25-OH) — Target 50-70 ng/mL, not just "above 30."
- B12 — Standard range starts too low. Optimal is upper third of range.
- Ferritin — Iron storage. Low = fatigue. Very high = inflammation or iron overload.
- RBC Magnesium — Serum magnesium is useless; most is intracellular.
- Zinc — Difficult to test accurately, but plasma zinc gives some signal.
- Folate — Important for methylation, especially with MTHFR variants.
Food Sensitivities
IgE allergies are immediate and obvious — hives, swelling, anaphylaxis. IgG sensitivities are delayed, subtle, and cumulative. They drive inflammation without dramatic symptoms.
- IgG Food Sensitivity Panel — Tests reactions to 96-200+ foods. Not perfect, but reveals hidden triggers.
- Elimination Diet — Gold standard. Remove common triggers for 30 days, reintroduce systematically.
Note: The medical establishment debates IgG testing validity. Functional medicine uses it routinely and finds it clinically useful. Your call whether to test or just eliminate and observe.
Gut Health
70% of your immune system is in your gut. Dysbiosis, leaky gut, and chronic GI inflammation affect everything.
- Comprehensive Stool Analysis (GI-MAP, GI Effects) — Bacteria, parasites, yeast, inflammation markers, digestive function.
- Zonulin — Marker for intestinal permeability ("leaky gut").
- Calprotectin — Inflammation in the gut lining.
Toxins / Environmental Load
Heavy metals, mold, and environmental chemicals accumulate. The body can handle some; it can't handle an endless load with no detox support.
- Heavy Metals (blood or urine) — Lead, mercury, arsenic, cadmium. Provoked urine test after chelation challenge is more revealing.
- Mycotoxins (urine) — Mold exposure markers.
- Organic Acids Test (OAT) — Metabolic byproducts indicating nutrient status, detox capacity, mitochondrial function, yeast/bacterial overgrowth.
How to Get These Tests
Option 1: Ask Your Doctor
Some doctors will order these if you ask. Many won't, or will order partial panels. Insurance may or may not cover.
Script: "I'd like a more comprehensive workup. Specifically, I want [test names]. I understand it may not be covered — I'm willing to pay out of pocket if needed."
If they refuse or condescend, find a different doctor.
Option 2: Direct-to-Consumer Labs
Order tests yourself, no doctor required:
- Ulta Lab Tests — Quest Diagnostics network
- Walk-In Lab — LabCorp network
- Life Extension — Member pricing on panels
- Marek Health — Focused on hormones and performance
Option 3: Functional Medicine / Integrative Doctor
These practitioners run comprehensive panels as standard practice. Expect to pay out of pocket; most don't take insurance. But they'll actually investigate root causes.
Option 4: Naturopath (ND)
Naturopathic doctors often have broader testing philosophy. Licensure varies by state.
Sources
The Point
You can't fix what you can't see.
Standard medicine shows you a narrow slice — just enough to rule out immediate crisis. It doesn't show you the accumulating load, the hidden triggers, the systems running suboptimally.
The tests exist. The information is available. But you have to ask for it — or order it yourself.
Every hidden stressor you find and eliminate is one less thing your body has to fight. Maybe none of them alone would have caused a problem. But they add up. And when something serious hits, you want your body fighting that — not also fighting the almond flour you thought was healthy.